Staphylococcus aureas versus Methicillin Resistant Staphylococcus aurea

From staphylococcus aureus to MRSAAbstractI investigated the difference between staph aureas and its highly bacteriumform of Methicillin-resistant staphylococcus aureas. I exercised books, websites, and studious projects to understand the topic at a molecular level. After researchingpenicillin, Staphylococcus aureas, and Methicillin-resistant Staphylococcus aureas, I plant that both the drug and the bacteria do enzymes as their defense and attackmechanism. Penicillin uses a -lactam resile as a substrate to clog the active site oftranspeptidase, and in defense, the bacteria uses -lactamase to disturbance down the -lactamring. I hope to continue research on super bacteria to determine whether or not othersuper bacteria such as Enterococcus faecium and Streptococcus pyogenes use the samedefenses. I found growing number of super bacteria both interesting and disconcerting.My terminus is that antibiotics and even antibacterials must be monitored more closelyif we wish to hold o ff the upper hand over bacteria.In 1928 when Alexander Fleming saw the bacteria-free ring of inhibition made byStaphylococcus aureus around Penicillium notatum (penicillin) in his petri dish, he musthave been shocked and thrilled. By 1940, penicillin was being produced for a very eagerpublic. 4 It was our miracle drug bacterial infections were a thing of the past. However,the use of penicillin was quickly abused, and problems arose. A target bacteria,Staphylococcus aureas soon learned to pommel the scientist who thought he had themconquered. MRSA, or Methicillin-resistant Staphylococcus aureas is very similar toStaphylococcus aureas, but it is no longer affected by penicillin or methicillin, the aroundcommon antibiotics... ...iel C., and Natalie C. J. Strynadka. Structure of SeMet Penicillin BindingProtein 2a From Methicillin Resistant Staphylococcus Aureus Strain 27r (TrigonalForm) At 2.45 a Resolution. (2002). Protein Data Bank. .4 Natural Products as Pharmaceuticals a Look At Penicillin. 20 July 2008.5 Strynadka, Natalie C. J., and Daniel Lim. Structural Basis of B-Lactam Resistance inMethicillin-Resistant Strains of Superbug Revealed. 2002. University ofBritish Columbia. 20 July 2008_sci_3.pdf.6 The Bacterial Cell Wall. 1995. The University of Texas, DPALM MEDIC. 20 July2008 .7 Weigelt, John A. MRSA. New York Informa Healthcare, 2008.